Sibutramine 15mg

Clinical Studies In Sibutramine

Introduction

A clinical study of Sibutramine is a trial to test the safety and efficacy of the drug on people, once it has been determined ‘safe’ during laboratory testing. As such Sibutramine will be tested in a clinical study on people of normal/average health who would be deemed to benefit from using it. Clinical studies can be conducted by pharmaceutical companies producing drugs, government organizations, universities or, indeed, any concerned group that can fund the study. To have true value a clinical study in Sibutramine will be carried out with concurrent studies of other ‘control’ groups.

The use of control groups in clinical studies

During any clinical study it is important to ensure that all possible factors relating to the efficacy of a drug are covered. To do this, in the case of appetite suppressants like Sibutramine, control groups would also be set up to provide comparative data. These control groups would not be given Sibutramine, some would be given an alternative and previously tested diet pill, others might be given a placebo, whilst a third control group might be given no drugs at all be tested on their ability to lose weight simply by dieting and exercising. In this way the possibility of any results merely being due to ‘chance’ are reduced. Finally, although Sibutramine is primarily used to help obese people lose weight, you may well find Sibutramine clinical studies into other areas such as using sibutramine to help quit smoking and keep your weight down.

Looking for Sibutramine clinical studies

Whilst finding the results of clinical studies in Sibutramine is very easy, actually understanding what they are saying can take rather more time. Enter something like ‘Sibutramine clinical studies’ into your favorite search engine and you will see returned well over a quarter of a million results. Unless you are 100% confident of the source of a piece of information on the internet, you should never just accept one version of it or the first in the list of results returned to you. Whilst the pharmaceutical company responsible for producing the drug, Abbot Laboratories in the case of Sibutramine, will always have reliable data from clinical studies of their product, you should at least compare what they say to another source from an independent university, governmental or other independent research authority.

Examples of results from clinical studies in Sibutramine

The most useful clinical studies in Sibutramine to read are those that list the comparative data obtained from control groups, rather than those that might only discuss how effective Sibutramine is in helping people lose weight. One clinical study you might come across compares the effectiveness Sibutramine with another weight loss pill, orlistat, in obesity management programs. This clinical study specifically outlines the importance of remaining compliant to a treatment regime of Sibutramine, that is to take the weight loss pill as prescribed and not being tempted to try and ‘cheat the system’. Clinical studies can be full of scientific/technical jargon and statistics but, in essence, this study concluded that Sibutramine was more effective in helping compliant obese patients in losing weight compared to the other drug. In the case of Sibutramine patients lost 10.5% of their body weight compared to just 7.6% for the other drug. (The trial took place over just under 4 months and, for those of you that are interested to know, the results are subject to statistical error of +/-2.9%.) Another clinical case study in Sibutramine compared the effectiveness of Sibutramine to a control group who were given a placebo and put on a controlled diet and exercise program. The people in the study were all clinically obese and some were morbidly obese. Over an 8 week period the placebo/control group lost, on average, 1.4kg whereas those on just 5mg a day of Sibutramine lost 2.9kg on average. However, the group taking Sibutramine was split into two sections, one taking 5mg a day and the other taking 20mg a day. Significantly the section taking 20mg a day of Sibutramine lost an incredible 5kg in 8 weeks! (Statistical errors for the previously quoted figures are: +/-2.1kg, +/-2.3kg and +/-2.7kg respectively.) Some of the group taking Sibutramine did leave the trial early due to suffering side-effects from taking the drug. You can read more about the side-effects of Sibutramine elsewhere in this series of articles on the appetite suppressant Sibutramine.